pacemaker activity造句

• Increase of ectopic pacemaker activity can occur when pseudoephedrine is used concomitantly with digitalis.
• Stretching GI muscles can affect the resting potentials of ICC and affect the frequency of pacemaker activity.
• Increased potassium conductance should stabilize membrane potential during ischemic insults, reducing the extent infarct and ectopic pacemaker activity.
• But this pacemaker activity is actually made by a group of cells that derive from the sinoatrial right venous sinus.
• Changes in electrolyte balance, or development of ectopic pacemaker activity, disrupt normal heart hypoxia, acidosis and drug toxicity.
• It can be considered a form of ectopic pacemaker activity that is unveiled by lack of other pacemakers to stimulate the ventricles.
• Normally, the pacemaker cells of the sinoatrial node discharge at the highest frequency and are thus dominant over other cells with pacemaker activity.
• Consequently, ANO1 activation is necessary for normal function of the ICC and its generated pacemaker activity in the smooth muscles of the intestine.
• Thus, minimally invasive TBX18 gene transfer creates physiologically relevant pacemaker activity in complete heart block, providing evidence for therapeutic somatic reprogramming in a clinically relevant disease model.
• The neuromodulator, substance P, activates TRPC3 / 7 channels inducing cellular currents that underlie rhythmic pacemaker activity in the brainstem, enhancing the regularity and frequency of respiratory rhythms, showing homology to the mechanism described in BG neurons.
• There are important physiological differences between nodal cells and ventricular cells; the specific differences in ion channels and mechanisms of polarization give rise to unique properties of SA node cells, most important, the spontaneous depolarizations necessary for the SA node's pacemaker activity.
• There are important physiological differences between excitatory cells and muscular cells; the specific differences in ion channels and mechanisms of polarization give rise to unique properties of excitatory cells, most importantly the spontaneous depolarization ( cardiac muscle automaticity ) necessary for the SAN pacemaker activity.
• Adenoviral TBX18 gene transfer could create biological pacemaker activity in vivo in a large-animal model of complete heart block . Biological pacemaker activity, originating from the intramyocardial injection site, was evident in TBX18-transduced animals starting at day 2 and persisted for the duration of the study ( 14 days ) with minimal backup electronic pacemaker use.
• Adenoviral TBX18 gene transfer could create biological pacemaker activity in vivo in a large-animal model of complete heart block . Biological pacemaker activity, originating from the intramyocardial injection site, was evident in TBX18-transduced animals starting at day 2 and persisted for the duration of the study ( 14 days ) with minimal backup electronic pacemaker use.